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thalassaemia major

Cooley's anemia or thalassaemia major  was first described in 1925 by the American pediatrician Thomas Cooley. 

haemoglobin

The name thalassaemia was coined by the Nobel Prize-winning pathologist George Whipple and the professor of pediatrics William Bradford. It derives from the Greek thalassa (sea) and -aemia (blood). Thalassaemia means "sea in the blood."

lab research
 
The gene for beta thalassaemia is  relatively more frequent in  the Mediterranean. Because of this, thalassaemia major has been called Mediterranean anemia.
 
thalassaemia blood
 

 
 
Research at PRI

The main research topic in the published literature of PRI is the new iron chelating drug Deferiprone (L1), which was discovered by G. J. Kontoghiorghes and is used worldwide in thalassaemia and other conditions of transfusional iron overload. Click on the following links to see the history of Deferiprone and recent related publications.

Relevant institute studies have been published in international journals. Click here for details.


The main areas of research interest and activity at the Postgraduate Research Institute include:
 
Medicine
Thalassaemia and other Haematological conditions
Nuclear Medicine
Psychiatric conditions
Metal toxicities
Metal deficiencies
Ethics

Biochemistry 
Metal Biochemistry  
Proteins in the transport and storage of metal ions 
Free Radicals
Antioxidants

Chemistry
Synthetic chemistry
Medicinal chemistry
Inorganic chemistry

Pharmacology 
Pharmacokinetics
Drug metabolism

Pharmaceuticals
Drug design and development
Metal chelating drugs
Orphan Drugs
Diagnostics

Environment
Hydrotechnology
Water treatment
Environmental pollution

Nutrition
All aspects
 

 
 
 

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Last update:
24 January 2006

 
 
POSTGRADUATE RESEARCH INSTITUTE Science, Technology, Environment and Medicine
3 Ammochostou Street, CY-3021 Limassol, Cyprus
Postal address: P.O. Box 51342, CY-3504 Limassol, Cyprus
Tel: +357 25 734 615, Fax: +357 25 395 926, Email:
kontoghiorghes.g.j@pri.ac.cy
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